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DEPARTMENT OF MOLECULAR BIOLOGY Print option in slimbox / lytebox? (info)
Sunday, 24 November 2019 23:07

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Miecznikowa 1, 02-096 Warszawa

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p>Director:
dr hab. Piotr Kozłowski
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phone: (4822) 55 43 108

Staff:
dr hab. Jan Fronk
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phone: (4822) 55 43 103

dr hab. Agnieszka Girstun
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phone: (4822) 55 43 111

dr Takao Ishikawa
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phone: (4822) 55 43 111

dr inż. Emilia Orzechowska
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phone: (4822) 55 43 111

prof. dr hab. Krzysztof Staroń
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dr Joanna Trzcińska-Danielewicz
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phone: (4822) 55 43 108

p. Ewa Urbaniak
phone: (4822) 55 43 111

Research areas:

  • Proteomes of eukaryotic cells. The research subjects are proteins from various cells, and which bind eukaryotic topoisomerase I. The goal of the research is the identification of these proteins and determination whether they influence the catalytic properties of topoisomerase I, as well as its sensitivity to anti-cancer Dr.ugs of the kamptothecine group.
  • Methylation of DNA and chromatine structure. The research concerns epigenetic mechanisms of the regulation of transcription in eukarya.
  • Signalling along the RAS/RAF/MAPK pathway. The research being performed is meant to determine the patterns of tissue expression of the HumER gene, which may be involved in signal transfer in the RAS/RAF/MAPK pathway, as well as the determination of the cellular localization of the HumER protein and the identification of proteins which interact with it in mammalian cells.